Новости за 15.11.2024

Viscosity blunts cell response to stiff matrices in agreement with a pull-and-hold model of molecular clutch-based mechanosensing.

A generative adversarial network can accurately reconstruct pan-cancer histology from a generalized latent space.

A spatiotemporal m6A imaging system was developed for live-cell visualization of m6A and its readers in SG stability.

Paleoecological records show that Aboriginal people burned wet forest to first settle in Tasmania 41,600 years ago.

Unlocking the power of force, CD40 employs mechanotransduction to fine-tune antibody-mediated immune responses.

An insertion mechanism of the ethynyl radical into a single bond challenges current perceptions of chemical reactivity.

BCAP is necessary to internalize BCR-bound antigens and antigen trafficking, BCR signal propagation, and antigen presentation.

Seasonal variability of Atlantic tropical cyclone activity is projected to increase, leading to more active hurricane seasons.

AVS100, a selective HDAC6 inhibitor, exhibits strong antitumoral effects via modulation of immune tumor microenvironment.

A resistant bacterial ribosome variant is outcompeted despite antibiotic pressure when Mg2+ is limited, exposing a vulnerability.

Haloarchaea use contractile injection systems to facilitate contact-dependent antagonism against other haloarchaea.

The brain uses pyruvate as an energy source, and mitochondrial pyruvate metabolism in nerve terminals controls neurotransmission.

Nano-electric pulse generator enables the dynamic control of electron density at the nanoscale region.

Advances in genomics, proteomics, and metabolomics have revealed associations between specific microbiota species in health and disease. However, the precise mechanism(s) of action for many microbiota species and molecules have not been fully elucidated, ...

Metabolic requirements vary during development, and our understanding of how metabolic activity influences cell specialization is incomplete. Here, we describe a switch from glutamine catabolism to synthesis required for erythroid cell maturation. ...

Oriented cell divisions are crucial for determining the overall morphology and size of plants, but what controls the onset and duration of this process remains largely unknown. Here, we identified a small molecule that activates root apical meristem (RAM)...

Wake up and smell the ashes, Ms. Washenko.

Dune: Prophecy is a much riskier bet than its studio seems to realize — one that could very well fail to pay off.

Republican Sen. Katie Britt (Ala.) is putting Columbia University, UCLA, and other schools on notice that the incoming GOP congressional majority plans to crack down on anti-Semitic demonstrations proliferating on college campuses.

The association says home sales in the region totalled 3,824 for the month, up from 2,659 in October 2023.

Kille says this whipper was actually in the "no fall zone" but his belayer reeled in a good armful of rope to keep him off the ground. 

John Collins scored 28 points and made a game-winning dunk with 6.4 seconds remaining to lift the Utah Jazz to a 115-113 win over the Dallas Mavericks in the NBA on Thursday night in Salt Lake City. The Mavericks had a final chance to tie or take the lead, but Naji Marshall missed a corner

Filmmaker Payal Kapadia's drama about three generations of women dealing with love, lust and loss in modern-day Mumbai is like a sneak attack on your soul

America believes it has made more than enough sacrifice on fossil fuels