Tabulae Paralytica: Mapping the biology of spinal cord injury in unprecedented detail

Scientists have achieved a significant research milestone in the field of spinal cord injuries -- mapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project 'Tabulae Paralytica'. Gr goire Courtine and his team have integrated cutting-edge cell and molecular mapping technologies with artificial intelligence to chart the complex molecular processes that unfold in each cell after spinal cord injuries (SCI). This seminal work not only identifies a specific set of neurons and genes that plays a key role for recovery but also proposes a successful gene therapy derived from its discoveries.