New switchable process for synthesizing 3-aminoindolines and 2'-aminoarylacetic acids from same substrate

Aniline or nitrogen-containing organic molecules like 3-aniline-substituted indoles commonly found in natural products have shown promising results as pharmaceutical contenders. The same goes for moieties such as 2-aminoaryl acetic acid scaffold which forms the fundamental structural motif of nonsteroidal anti-inflammatory drugs such as diclofenac which inhibits COX-2 to relieve pain and inflammation.