Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease

Allogenic hematopoietic cell transplantation (allo-HCT) involves transferring healthy donor stem cells to recipients with conditions such as blood cancer, bone marrow failure, or certain genetic blood disorders. Acute graft-versus-host disease (aGVHD) is a common complication, where the donor's immune cells attack the recipient's tissues.