General Hospital's Cameron Mathison & Wife Vanessa Split After 22 Years Together

General Hospital‘s Cameron Mathison and his wife, Vanessa Mathison, are separating.

The 54-year-old actor and 57-year-old model have been married for 22 years.

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“After 22 years of marriage, we have made the difficult decision to part ways. We enter this new chapter with deep love, kindness, and respect for each other. We hold gratitude in our hearts for the wonderful years we shared together,” they said in a statement to ET.

They added, “Our children have been and will continue to be our highest priority, and we will forever share in our devotion and love for them.”

The couple have two kids together: a son Lucas, 21, and daughter Leila, 18.

Cameron appeared on almost 300 episodes of General Hospital, and during their marriage, Vanessa appeared on three episodes herself.