Improving resolution and reducing noise in fluorescence microscopy with ensured fidelity

Fluorescence microscopy is a cornerstone of modern biological imaging, allowing scientists to study cells and their processes in real time. However, limitations in resolution and noise levels can hinder the clarity and detail of these images. Moreover, the laser illumination could cast toxicity on cells and cause photo-bleaching, further confining the signal-to-noise ratio (SNR) in live-cell imaging.