Use of C-reactive protein to tailor antibiotic use: a systematic review and meta-analysis

Journal List BMJ Open v.8(12); 2018 PMC6318522 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more: PMC Disclaimer | PMC Copyright Notice BMJ Open. 2018; 8(12): e022133. Published online 2018 Dec 22. doi:10.1136/bmjopen-2018-022133PMCID: PMC6318522PMID: 30580258Dara Petel,1 Nicholas Winters,2 Genevieve C Gore,3 Jesse Papenburg,4,5 Marc Beltempo,6 Jacques Lacroix,7 and Patricia S Fontela5,8Author information Article notes Copyright and License information PMC DisclaimerAssociated DataSupplementary MaterialsAbstractBackground and objectivesC-reactive protein (CRP) has been proposed to guide the use of antibiotics. However, study results are controversial regarding the benefits of such a strategy. We synthesised the evidence of CRP-based algorithms on antibiotic treatment initiation and on antibiotic treatment duration in adults, child...