Flavonoid powerhouse: Kaempferol's role in taming allergic responses

Food allergies affect millions of people worldwide, and flavonoids are promising natural compounds to help modulate the immune response and treat inflammation caused by these allergies. In a recent study, researchers have identified that kaempferol, a flavonoid, produces an anti-inflammatory effect through regulatory T-cell development. This occurred through increased RADLH2 expression in dendritic cells via AhR-mediated and PU.1/IRF-4 dependent mechanisms. Additionally, kaempferol suppressed several allergic symptoms in mice with food allergies.