Researchers reveal mechanisms underlying Sjögren's disease

Researchers are closer to understanding what drives the autoimmune disorder Sj gren's disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon. Their latest study finds that impaired regulatory T cells are a critical contributing factor to Sj gren's disease in both mice and humans, and identifies an existing rheumatology drug as a promising therapy for the disease.