Povidone Iodine vs Chlorhexidine Gluconate for Preoperative Antisepsis

To the Editor A recent study in JAMA comparing povidone iodine with chlorhexidine gluconate for preoperative skin antisepsis effectively informed the clinical decision-making process in surgical settings to prevent SSIs. However, while the study addressed the primary objective, several ancillary considerations relevant to the surgical community warrant further exploration.