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Новости за 20.05.2024

Plos.org 
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A UL26-PIAS1 complex antagonizes anti-viral gene expression during Human Cytomegalovirus infection

by Jessica Ciesla, Kai-Lieh Huang, Eric J. Wagner, Joshua Munger

Viral disruption of innate immune signaling is a critical determinant of productive infection. The Human Cytomegalovirus (HCMV) UL26 protein prevents anti-viral gene expression during infection, yet the mechanisms involved are unclear. We used TurboID-driven proximity proteomics to identify putative UL26 interacting proteins during infection to address this issue. We find that UL26 forms a complex with several immuno-regulatory proteins... Читать дальше...

Plos.org 
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Corporate restructuring and firm performance in Vietnam: The moderating role of digital transformation

by Duc Hong Vo, Anh The Vo, Co Thi-Huyen Dinh, Ngoc Phu Tran

In the digital age, firms should continually innovate and adapt to remain competitive and enhance performance. Innovation and adaptation require firms to take a holistic approach to their corporate structuring to ensure efficiency and effectiveness to stay competitive. This study examines how corporate restructuring impacts firm performance in Vietnam. We then investigate the moderating role of digital transformation in the corporate restructuring–firm performance nexus. Читать дальше...

Зумеры запустили безумный тренд – прыгать в мусорные баки
5 лучших масок для восстановления волос после солнца
Наталья Страшнова стала ведущей программы «Формула Верхневолжья».
Кейт Сигел снимется в черной комедии «Будь ты проклят, если сделаешь это»
В Магнитогорске из реки выловили женский труп с привязанным к нему грузом
«Король Лир» Сергея Потапова стал победителем VIII фестиваля нового российского кино «Горький fest»
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Factors associated with oral health care behavior of people with type 2 diabetes mellitus: A hospital-based, cross-sectional study

by Kamonchanok Sairat, Nitikorn Phoosuwan

Background

Oral healthcare behavior determines oral health status and the incidence of oral diseases. People with type 2 diabetes mellitus (T2DM) are at-risk of having low oral healthcare behavior and disease-related oral health.

Objective

To investigate the oral health status and factors associated with oral healthcare behavior among people with T2DM in Thailand.

Methods

In total, 401 people with T2DM participated in the study based... Читать дальше...

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Tolerance for corruption and descriptive social norm: An experimental study of embezzlement

by Sen Tian, Liangfo Zhao

Public tolerance for corruption within a society significantly influences the prevalence of corrupt practices, but less is known about how this tolerance evolves with social norms. This paper presents experimental evidences demonstrating that the descriptive social norm indicating widespread corruption can lead to increased tolerance for corruptive acts. We introduce an asymmetric information ultimatum game to simulate the interactions between embezzlers and citizens. Читать дальше...

Ночные грозы и дожди на выходных пообещали жителям Новосибирска
В Новосибирске полным ходом идет строительство нового эко-квартала: в него можно выгодно инвестировать
Томич перевел 1,5 млн рублей на "безопасные счета"
Строение горело в Палкинском районе ночью
Военно-исторический фестиваль пройдет в Островском районе 21 июля
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A theory of oral healthcare decision-making in Appalachia

by R. Constance Wiener, Christopher Waters, Ruchi Bhandari

Introduction

People make oral healthcare decisions regardless of having partial information, misinformation, sources that deliberately mislead, or information that is culturally influenced. This is particularly true in the Appalachian culture where oral healthcare decision-making practices are not well understood by researchers and dental professionals. Despite efforts to improve dental care utilization, the Appalachia region remains low in oral healthcare utilization. Читать дальше...

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Subjective perception of visual field defects using random noise-moving images in patients with glaucoma: A comparison of computer graphics and analog noises

by Arata Inoue, Eiko Koike, Naoyuki Maeda, Chota Matsumoto

Purpose

Random noise-moving images (noises) can make glaucoma patients with no subjective symptoms aware of visual field abnormalities. To explore this concept, we developed a noise using computer graphics (CG) and investigated the difference in the subjective perception of visual field abnormalities between CG and conventional analog noises.

Methods

We enrolled individuals with glaucoma (205 eyes), preperimetric glaucoma (PPG; 19 eyes), and normal eyes (35 eyes). Читать дальше...

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Identifying meta-research with researchers as study subjects: Protocol for a scoping review

by Gregory Laynor, Elizabeth R. Stevens

Background

Meta-research in which researchers are the study subjects can illuminate how to better support researchers and enhance the development of research capacity. Comprehensively compiling the literature in this area can help define best practices for research capacity development and reveal gaps in the literature. However, there are challenges to assessing and synthesizing the breadth of the meta-research literature produced.

Methods

In this article... Читать дальше...

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Determinants of social participation in people with disability

by Tugce Pasin, Bilinc Dogruoz Karatekin

Purpose

In this study, it is aimed to determine personal wellbeing and social participation levels across different physical disability types and levels of mobility.

Methods

A sample of 85 individuals with physical disabilities, excluding those with mental disabilities were included. Sociodemographics, mobility of the participants, cause, duration of disability were recorded. Personal Wellbeing Index-Adult (PWI-A) scale was used for the assessment... Читать дальше...