Home range, habitat use and capture-release of translocated leopards in Gir landscape, Gujarat, India
by Mohan Ram, Aradhana Sahu, Nityanand Srivastava, Rohit Chaudhary, Lahar Jhala, Yashpal Zala, Meena Venkataraman
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by Mohan Ram, Aradhana Sahu, Nityanand Srivastava, Rohit Chaudhary, Lahar Jhala, Yashpal Zala, Meena Venkataraman
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by Stephen Estelle, Kenzo Uhlig, Leonardo Zapata-Fonseca, Sébastien Lerique, Brian Morrissey, Rai Sato, Tom Froese
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by Wolde Facha, Takele Tadesse, Eskinder Wolka, Ayalew Astatkie
BackgroundHigh viral load during pregnancy and breastfeeding period is the risk factor for vertical transmission of human immunodeficiency virus (HIV). Currently, Dolutegravir (DTG)-based regimens are recommended to attain adequate viral load suppression (VLS) among women. However, its effect on VLS has not been investigated among women in PMTCT care in Ethiopia.
ObjectiveThis study aimed to investigate the rate of... Читать дальше...
by Ilona Bass, Elizabeth Bonawitz
A great deal of research has demonstrated how children’s exploration is driven by opportunities for learning. However, less work has investigated how individual differences across children and their environmental contexts relate to patterns in playful exploration. We performed a “mega-analysis” in which we pooled preschool-aged children’s play data from four past experiments in our lab (N = 278; M(age) = 56 months) and correlated play behaviors with age and socioeconomic status (median income... Читать дальше...
by Jasmin Bhawra, M. Claire Buchan, Brenda Green, Kelly Skinner, Tarun Reddy Katapally
by Ibrahim Halil Aslan, Julie D. Pourtois, Andrew J. Chamberlin, Kaitlyn R. Mitchell, Lorenzo Mari, Kamazima M. Lwiza, Chelsea L. Wood, Erin A. Mordecai, Ao Yu, Roseli Tuan, Raquel Gardini Sanches Palasio, Antônio M. V. Monteiro, Devin Kirk, Tejas S. Athni, Susanne H. Sokolow, Eliezer K. N’Goran, Nana R. Diakite, Mamadou Ouattara, Marino Gatto, Renato Casagrandi, David C. Little, Reed W. Ozretich, Rachel Norman, Fiona Allan, Andrew S. Brierley, Ping Liu, Thiago A. Pereira, Giulio A. De Leo
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by Keon-Woong Yoon, Ki Back Chu, Gi-Deok Eom, Jie Mao, Fu-Shi Quan
Leishmania donovani surface glycoprotein 63 (GP63) is a major virulence factor involved in parasite escape and immune evasion. In this study, we generated virus-like particles (VLPs) expressing L. donovani GP63 using the baculovirus expression system. Mice were intramuscularly immunized with GP63-VLPs and challenged with L. donovani promastigotes. GP63-VLP immunization elicited higher levels of L. donovani antigen-specific serum antibodies and enhanced splenic B cell... Читать дальше...
by Adnan Ahmad, Fawad Inayat, Noor Ullah, Shaista Rasul, Shehnaz Bakhtiar, Zar Shad, Zakir Ahmad
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by Rita Ting, Borame L. Dickens, Riona Hanley, Alex R. Cook, Ellyana Ismail
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by Gladymar Pérez Chacón, Marie J. Estcourt, James Totterdell, Julie A. Marsh, Kirsten P. Perrett, Dianne E. Campbell, Nicholas Wood, Michael Gold, Claire S. Waddington, Michael O’ Sullivan, Sonia McAlister, Nigel Curtis, Mark Jones, Peter B. McIntyre, Patrick G. Holt, Peter C. Richmond, Tom Snelling
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by Christine W. Gao, WanYing. Lin, Ryan C. Riddle, Sheetal. Chopra, Jiyoung. Kim, Leandros. Boukas, Kasper D. Hansen, Hans T. Björnsson, Jill A. Fahrner
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by Kathleen Tsung, Kristie Q. Liu, Jane S. Han, Krutika Deshpande, Tammy Doan, Yong-Hwee Eddie Loh, Li Ding, Wentao Yang, Josh Neman, Yali Dou, Frank J. Attenello
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by Wei Du, Adya Verma, Qianlin Ye, Wen Du, Sandy Lin, Atsushi Yamanaka, Ophir D. Klein, Jimmy K. Hu
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by Xiangting Li, Tom Chou
Cellular signaling, crucial for biological processes like immune response and homeostasis, relies on specificity and fidelity in signal transduction to accurately respond to stimuli amidst biological noise. Kinetic proofreading (KPR) is a key mechanism enhancing signaling specificity through time-delayed steps, although its effectiveness is debated due to intrinsic noise potentially reducing signal fidelity. In this study, we reformulate the theory of kinetic proofreading... Читать дальше...
by Sebastian Salwig, Jakob Drefs, Jörg Lücke
Conventional and electron microscopy visualize structures in the micrometer to nanometer range, and such visualizations contribute decisively to our understanding of biological processes. Due to different factors in recording processes, microscopy images are subject to noise. Especially at their respective resolution limits, a high degree of noise can negatively effect both image interpretation by experts and further automated processing. However... Читать дальше...
by Md Zulfikar Ali, Sunil Guharajan, Vinuselvi Parisutham, Robert C. Brewster
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by Florian Bolenz, Thorsten Pachur
Younger and older adults often differ in their risky choices. Theoretical frameworks on human aging point to various cognitive and motivational factors that might underlie these differences. Using a novel computational model based on the framework of resource rationality, we find that the two age groups rely on different strategies. Importantly, older adults did not use simpler strategies than younger adults, they did not select among fewer strategies, they did not make more errors... Читать дальше...
by Diego Andrés Contreras, Giulia Cencetti, Alain Barrat
Contagion processes, representing the spread of infectious diseases, information, or social behaviors, are often schematized as taking place on networks, which encode for instance the interactions between individuals. The impact of the network structure on spreading process has been widely investigated, but not the reverse question: do different processes unfolding on a given network lead to different infection patterns? How do the... Читать дальше...
by Roberth Anthony Rojas Chávez, Mohammad Fili, Changze Han, Syed A. Rahman, Isaiah G. L. Bicar, Sullivan Gregory, Annika Helverson, Guiping Hu, Benjamin W. Darbro, Jishnu Das, Grant D. Brown, Hillel Haim
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by Mollie Virgo, Brian Thomas Ho, Serge Mostowy
Zebrafish are often used to model host-pathogen interactions, but few models of natural virus infection have been established. A new study in PLOS Biology shows that metatranscriptomics and cohousing experiments can uncover a natural pathogenic virus of zebrafish for laboratory study. Zebrafish are often used to model host-pathogen interactions, but few models of natural virus infection have been established. This Primer explores a new study... Читать дальше...
by E. J. Milner-Gulland
Existing power imbalances and injustices could be exacerbated by large flows of international funding for nature recovery. Conservationists are still grappling with what social justice means in practice; a major shift in mindset is required. Conservationists are still grappling with what social justice means in practice. This Perspective argues that a major shift in mindset is required in order to achieve socially just, rights-based conservation, and that shift needs to happen now.
by Laura E. Burnett, Peter Koppensteiner, Olga Symonova, Tomás Masson, Tomas Vega-Zuniga, Ximena Contreras, Thomas Rülicke, Ryuichi Shigemoto, Gaia Novarino, Maximilian Joesch
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by Kayla J. Ripple, Charlotte Hudson, Emily Knight, Jason P. Landrum, Victoria Bell, Sarah L. Close
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by Vanessa M. Adams
There has been an increasingly prevalent message that data regarding costs must be included in conservation planning activities to make cost-efficient decisions. Despite the growing acceptance that socioeconomic context is critical to conservation success, the approaches to embedded economic and financial considerations into planning have not significantly evolved. Inappropriate cost data is frequently included in decisions, with the potential of compromising biodiversity and social outcomes. Читать дальше...