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Новости за 30.07.2024

Plos.org 

The LuxO-OpaR quorum-sensing cascade differentially controls Vibriophage VP882 lysis-lysogeny decision making in liquid and on surfaces

by Francis J. Santoriello, Bonnie L. Bassler

Quorum sensing (QS) is a process of cell-to-cell communication that bacteria use to synchronize collective behaviors. QS relies on the production, release, and group-wide detection of extracellular signaling molecules called autoinducers. Vibrios use two QS systems: the LuxO-OpaR circuit and the VqmA-VqmR circuit. Both QS circuits control group behaviors including biofilm formation and surface motility. The Vibrio parahaemolyticus temperate phage φVP882 encodes a VqmA homolog (called VqmAφ). Читать дальше...

Plos.org 

Using deep learning to decipher the impact of telomerase promoter mutations on the dynamic metastatic morpholome

by Andres J. Nevarez, Anusorn Mudla, Sabrina A. Diaz, Nan Hao

Melanoma showcases a complex interplay of genetic alterations and intra- and inter-cellular morphological changes during metastatic transformation. While pivotal, the role of specific mutations in dictating these changes still needs to be fully elucidated. Telomerase promoter mutations (TERTp mutations) significantly influence melanoma’s progression, invasiveness, and resistance to various emerging treatments, including chemical inhibitors... Читать дальше...

Plos.org 

Hyphae of the fungus Aspergillus nidulans demonstrate chemotropism to nutrients and pH

by Riho Yamamoto, Hinata Miki, Ayaka Itani, Norio Takeshita

The importance of fungi in ecological systems and pathogenicity hinges on their ability to search for nutrients, substrates, and hosts. Despite this, the question of whether fungal hyphae exhibit chemotropism toward them remains largely unresolved and requires close examination at the cellular level. Here, we designed a microfluidic device to assess hyphal chemotropism of Aspergillus nidulans in response to carbon and nitrogen sources, as well as pH. Читать дальше...

The Planetary Society 

Does Jupiter protect Earth from asteroids and comets?

Jupiter has often been thought to protect the inner Solar System from asteroids and comets, but new research has shown that the giant planet may actually increase the risk of an impact.

Autoblog.com 

14 thoughts about the 2024 Fiat 500e, one pink, the other an Italian tomato

Filed under: Green,Fiat,Electric,Road Tests

Continue reading 14 thoughts about the 2024 Fiat 500e, one pink, the other an Italian tomato

14 thoughts about the 2024 Fiat 500e, one pink, the other an Italian tomato originally appeared on Autoblog on Tue, 30 Jul 2024 10:00:00 EDT. Please see our terms for use of feeds.

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SharpMagazine.com 

Cocktail of the Week: Bee’s Knees

Sweet, tart, and refreshing all in one mouthful.

The post Cocktail of the Week: Bee’s Knees appeared first on Sharp Magazine.