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Новости за 20.08.2024

Plos.org 

Multiple sclerosis and abnormal spermatozoa: A bidirectional two-sample mendelian randomization study

by Bo Li, Lingang Zhang, Qi Li, Jianhua Zhang, Wei Wang, Jianwen Quan

Objective

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, and previous observational epidemiological studies have suggested an association between MS and male infertility; male infertility due to sperm abnormalities may result from a number of aetiological factors, such as genetics, autoimmune factors, etc., and there are currently no studies to assess whether MS is associated with sperm abnormalities in men. Читать дальше...

Plos.org 

Feasibility and reliability of online vs in-person cognitive testing in healthy older people

by Sol Morrissey, Rachel Gillings, Michael Hornberger

Background

Early evidence in using online cognitive assessments show that they could offer a feasible and resource-efficient alternative to in-person clinical assessments in evaluating cognitive performance, yet there is currently little understanding about how these assessments relate to traditional, in-person cognitive tests.

Objectives

In this preliminary study, we assess the feasibility and reliability of NeurOn, a novel online cognitive assessment tool. Читать дальше...

Plos.org 

Interregional circulation of credit resources and company innovation

by Xinglin Liu, Yu Chen, Yan Xiong, Yanlin Wu

Although the impact of interest rates, repayment periods, and loan scales on loan consequences has been extensively studied, little attention has been paid to the geographical distance involved in loan transactions. This study collects the addresses of borrowing companies, listed companies, and banks. Nonlocal loans can be distinguished because the regional segmentations in the lending industry reflect the features of provincial boundaries. Using... Читать дальше...

Plos.org 

Implementing a multi-cycle datapath with Liquid Marbles

by Sandro Erba, Luca Cavenaghi, Claudio Zandron

Liquid Marbles are liquid droplets encapsulated by hydrophobic powder particles; due to their non-wetting nature, they allow to manipulate liquids efficiently. Literature highlighted their potential to be employed as micro-reactors, micro-containers for growing micro-organisms and cells, micro-fluidics devices, and have also been used in the framework of unconventional computing. In this work, we discuss a theoretical implementation of all required... Читать дальше...

Plos.org 

The impact of digital financial inclusion on bank performance: An exploration of mechanisms of action and heterogeneity

by Jing Zhao, Congqi Wang, Haslindar Ibrahim, Yanpeng Chen

The use of digital technology by banks and other financial institutions to facilitate financial inclusion is referred to as digital financial inclusion. This fusion of digital finance and traditional banking methods has the potential to impact banks’ operational effectiveness. This study uses the panel effects model to examine the link between digital financial inclusion and bank performance in 30 Chinese provinces from 2012 to 2021. Читать дальше...

Plos.org 

CHRM3 (rs2165870) gene polymorphism is related to postoperative vomiting in female patients undergoing laparoscopic surgery. Prospective observational study

by Meng Cai, Lin Gan, Jing Li, Xiaofeng Lei, Jin Yu

Background

Postoperative nausea and vomiting are common complications after surgery, and female patients are more likely to experience these adverse events. The goal of this study was to explore the relationship between the CHRM3 rs2165870 polymorphism and postoperative vomiting incidence in female patients who underwent laparoscopic surgery.

Methods

Two hundred female patients who underwent elective laparoscopic surgery with subsequent... Читать дальше...

Plos.org 

Wild salmon migration routes influence sea lice infestations: An agent-based model predicting farm-related infestations on juvenile salmon

by Jaewoon Jeong, Gregor McEwan

This study presents an Agent-Based Model (ABM) simulation to assess the impact of varying migration routes on sea lice (Caligus clemensi) infestation levels in juvenile wild sockeye salmon (Oncorhynchus nerka) in the Discovery Islands, British Columbia, Canada. This research highlights the importance of migratory routes in determining the extent of exposure to sea lice originating from nearby salmon farms. Three northward out-migration routes were modelled... Читать дальше...

Plos.org 

KIC (ketoisocaproic acid) and leucine have divergent effects on tissue insulin signaling but not on whole-body insulin sensitivity in rats

by Gagandeep Mann, Stephen Mora, Olasunkanmi A. John Adegoke

Plasma levels of branched-chain amino acids and their metabolites, the branched-chain ketoacids are increased in insulin resistance. Our previous studies showed that leucine and its metabolite KIC suppress insulin-stimulated glucose uptake in L6 myotubes along with the activation of the S6K1-IRS-1 pathway. Because other tissue and fiber types can be differentially regulated by KIC, we analyzed the effect of KIC gavage on whole-body... Читать дальше...

Athletics Nation 

Elephant Rumblings: Nick Kurtz promoted to Double-A

Kevin Jairaj-USA TODAY Sports

MLB news roundup

Good morning Athletics Nation!

We learned yesterday afternoon that the club would be promoting top prospect Nick Kurtz all the way to Double-A, courtesy of Martin Gallegos:

A’s 2024 first round pick Nick Kurtz is being promoted to Double-A Midland, per GM David Forst.

— Martín Gallegos (@MartinJGallegos) August 20, 2024

It’s an aggressive promotion for the #4 overall pick in the 2024 MLB Draft. The Wake Forrest... Читать дальше...