by Huynh Thi Phuong, Nguyen Ha Thao Vy, Nguyen Thi Le Thanh, Maxine Tan, Erwin de Bruin, Marion Koopmans, Maciej F. Boni, Hannah E. Clapham
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by Winnie Kibone, Andrew Weil Semulimi, Richard Kwizera, Felix Bongomin
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by Marcos de Abreu Almeida, Lilian Cristiane Baeza, Leandro B. R. Silva, Andréa Reis Bernardes-Engemann, Fernando Almeida-Silva, Rowena Alves Coelho, Iara Bastos de Andrade, Dario Corrêa-Junior, Susana Frases, Rosely Maria Zancopé-Oliveira, Alexandre Alanio, Carlos Pelleschi Taborda, Rodrigo Almeida-Paes
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by Mikiko Inaki, Takamasa Higashi, Satoru Okuda, Kenji Matsuno
Complex organ structures are formed with high reproducibility. To achieve such intricate morphologies, the responsible epithelium undergoes multiple simultaneous shape changes, such as elongation and folding. However, these changes have typically been assessed separately. In this study, we revealed how distinct shape changes are controlled during internal organ morphogenesis. The Drosophila embryonic hindgut undergoes left-right... Читать дальше...
by Sarah E. Copeland, Santina M. Snow, Jun Wan, Kristina A. Matkowskyj, Richard B. Halberg, Beth A. Weaver
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by Brandon J. Thio, Nathan D. Titus, Nicole A. Pelot, Warren M. Grill
Unmyelinated C-fibers constitute the vast majority of axons in peripheral nerves and play key roles in homeostasis and signaling pain. However, little is known about their ion channel expression, which controls their firing properties. Also, because of their small diameters (~ 1 μm), it has not been possible to characterize their membrane properties using voltage clamp. We developed a novel library of isoform-specific ion... Читать дальше...
by Lianghong Chen, Zi Huai Huang, Yan Sun, Mike Domaratzki, Qian Liu, Pingzhao Hu
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by Jaspreet Ishar, Yee Man Tam, Simon Mages, Johanna Klughammer
Spatio-molecular data and microscopy images provide complementary information, essential to study structure and function of spatially organised multicellular systems such as healthy or diseased tissues. However, aligning these two types of data can be challenging due to distortions and differences in resolution, orientation, and position. Manual registration is tedious but may be necessary for challenging samples as well as for... Читать дальше...
by Blandine Moucaud, Elodie Prince, Elia Ragot, Yoan Renaud, Krzysztof Jagla, Guillaume Junion, Cedric Soler
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By Jesse Published: October 07th, 2024
New computer simulations show how a now-frozen ocean of water mixed with dirt and rock could explain geological features on Ceres' surface.
Graham asked me if I'd discovered what the metaphor in Metaphor: ReFantazio might be, and I replied, "I don't know haha", or something along those lines. Having given it more thought, I think there are two metaphors: 1) It plays quite like Persona. 2) Its story is like a commentary on our society… or something to that effect.
Читать дальше...America is always on the verge of finally having "honest government." Of course, what passes for “honest government” is a government that efficiently takes wealth from productive people and transfers it to those who are politically-connected.
Discover top trends, challenges and a step-by-step process to optimize and futureproof your images and videos for search.
It’s been a long wait, but our favorite neuroscience expert turned FBI consultant is back! The Irrational Season 2 Episode 1 …
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Last weekend, we warned readers that according to the latest data from Goldman Sachs, a massive short squeeze in energy stocks was on deck. Specifically we noted that at a time when funds were the most short oil on record, the broader energy space "was the most net sold sector" on the Goldman US Prime book, "driven entirely by short sales, which outpaced long buys (6.4 to 1)." And here, we said, was "the hint to the next mega squeeze" as the recent short selling in energy was the largest in over 5 years. Читать дальше...
by Diana C. de Oliveira, Hani Cheikh Sleiman, Kelly Payette, Jana Hutter, Lisa Story, Joseph V. Hajnal, Daniel C. Alexander, Rebecca J. Shipley, Paddy J. Slator
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by Fan Xia, Yanni Xiao, Junling Ma
Non-pharmaceutical interventions (NPIs) are effective in mitigating infections during the early stages of an infectious disease outbreak. However, these measures incur significant economic and livelihood costs. To address this, we developed an optimal control framework aimed at identifying strategies that minimize such costs while ensuring full control of a cross-regional outbreak of emerging infectious diseases. Our approach uses a spatial SEIR model with interventions for the epidemic process... Читать дальше...
by Marta Mackowiak, Bartosz Adamczyk, Marta Szachniuk, Tomasz Zok
RNA molecules, essential for viruses and living organisms, derive their pivotal functions from intricate 3D structures. To understand these structures, one can analyze torsion and pseudo-torsion angles, which describe rotations around bonds, whether real or virtual, thus capturing the RNA conformational flexibility. Such an analysis has been made possible by RNAtango, a web server introduced in this paper, that provides a trigonometric perspective on RNA 3D structures... Читать дальше...
You don't have to work in retail or health care to learn from what they're doing to leverage the power of artificial intelligence.
The sandwich was a massive hit in the United Kingdom, selling out in just 10 days during its limited run in 2022.
This gorgeous Greek island will give you the perfect autumn getaway.
Even marathon runners can be lazy and inconsistent.
The last time anyone drove on the Moon was way back in 1972 when the astronauts of Apollo 17 took the Lunar Roving Vehicle for one last spin. Now, NASA is plotting a return to the Moon’s surface that will include taking an all-new lunar rover with it, and it’s just started testing out prototypes for its latest Moon…
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Marcus Rashford has endured a rocky relationship with Erik ten Hag at Man Utd but could be handed a fresh start if Thomas Tuchel takes over as manager.
