Stable developmental patterns of gene expression without morphogen gradients
by Maciej Majka, Nils B. Becker, Pieter Rein ten Wolde, Marcin Zagorski, Thomas R. Sokolowski
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by Maciej Majka, Nils B. Becker, Pieter Rein ten Wolde, Marcin Zagorski, Thomas R. Sokolowski
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by Jan Stasinski, Halgurd Taher, Jil Mona Meier, Michael Schirner, Dionysios Perdikis, Petra Ritter
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by Lalit Pandey, Donsuk Lee, Samantha M. W. Wood, Justin N. Wood
How do newborns learn to see? We propose that visual systems are space-time fitters, meaning visual development can be understood as a blind fitting process (akin to evolution) in which visual systems gradually adapt to the spatiotemporal data distributions in the newborn’s environment. To test whether space-time fitting is a viable theory for learning how to see, we performed parallel controlled-rearing experiments on newborn chicks and deep neural networks (DNNs)... Читать дальше...
by Mark A. Orloff, Dongil Chung, Xiaosi Gu, Xingchao Wang, Zhixian Gao, Guiding Song, Chandana Tatineni, Shuai Xu, Brooks Casas, Pearl H. Chiu
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by Yuqian Liu, Yan Chen, Huanwen Wu, Xuanping Zhang, Yuqi Wang, Xin Yi, Zhiyong Liang, Jiayin Wang
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by Meng Yuan, Seppe Goovaerts, Michiel Vanneste, Harold Matthews, Hanne Hoskens, Stephen Richmond, Ophir D. Klein, Richard A. Spritz, Benedikt Hallgrimsson, Susan Walsh, Mark D. Shriver, John R. Shaffer, Seth M. Weinberg, Hilde Peeters, Peter Claes
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by Nisha Ann Viswan, Alexandre Tribut, Manvel Gasparyan, Ovidiu Radulescu, Upinder S. Bhalla
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by Adrián F. Amil, Albert Albesa-González, Paul F. M. J. Verschure
Theta-band oscillations (3–8 Hz) in the mammalian hippocampus organize the temporal structure of cortical inputs, resulting in a phase code that enables rhythmic input sampling for episodic memory formation and spatial navigation. However, it remains unclear what evolutionary pressures might have driven the selection of theta over higher-frequency bands that could potentially provide increased input sampling resolution. Here... Читать дальше...
by Michiel Vanslambrouck, Wim Thiels, Jef Vangheel, Casper van Bavel, Bart Smeets, Rob Jelier
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by Jonathan M. Werner, Jesse Gillis
Human neural organoids offer an exciting opportunity for studying inaccessible human-specific brain development; however, it remains unclear how precisely organoids recapitulate fetal/primary tissue biology. We characterize field-wide replicability and biological fidelity through a meta-analysis of single-cell RNA-sequencing data for first and second trimester human primary brain (2.95 million cells, 51 data sets) and neural organoids (1.59 million cells, 173 data sets). Читать дальше...
by Xin Yuan, Hailiang Li, Fang Guo
Organisms detect temperature signals through peripheral neurons, which relay them to central circadian networks to drive adaptive behaviors. Despite recent advances in Drosophila research, how circadian circuits integrate temperature cues with circadian signals to regulate sleep/wake patterns remains unclear. In this study, we used the FlyWire brain electron microscopy connectome to map neuronal connections, identifying lateral posterior neurons LPNs as... Читать дальше...
by Sarah Wettstadt, Francisco J. Marcos-Torres, Joaquín R. Otero-Asman, Alicia García-Puente, Álvaro Ortega, María A. Llamas
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by Rosanna C. T. Wright, A. Jamie Wood, Michael J. Bottery, Katie J. Muddiman, Steve Paterson, Ellie Harrison, Michael A. Brockhurst, James P. J. Hall
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by János Brunner, Antónia Arszovszki, Gergely Tarcsay, János Szabadics
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by Xitong Chen, Stephanie C. Leach, Juniper Hollis, Dillan Cellier, Kai Hwang
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by Xiaoyu Tian, Hanyu Wang, Song Liu, Wei Liu, Kaiyue Zhang, Xiaohan Gao, Qingchao Li, Huijie Zhao, Liangran Zhang, Peiwei Liu, Min Liu, Youjun Wang, Xueliang Zhu, Rutao Cui, Jun Zhou
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by Roy Novoselsky, Yotam Harnik, Oran Yakubovsky, Corine Katina, Yishai Levin, Keren Bahar Halpern, Niv Pencovich, Ido Nachmany, Shalev Itzkovitz
Читать дальше...The culmination of the 2024 presidential election between Vice President Kamala Harris and President-elect Donald Trump resulted in big numbers for Fox News and audience erosion for MSNBC and CNN. Trump's win was a big boon for FNC as it commanded the largest cable news share in its history with 62% of the cable news...
It's been a busy year for Disney Advertising and the company's streaming platforms. In 2024, Disney saw 40% of its total upfront dollars earmarked for streaming and digital offerings, and it has taken steps throughout the year to bolster that side of the business, including now working with nearly 40 demand-side platforms, making investments in...
Image: Bepi, Mio and MTM greet Mercury for the fifth time
The Ministry of Interior announced an increase in security measures ahead of the upcoming holiday season, focusing on the student celebrations on December 8, as well as the Christmas and New Year holidays. Law enforcement presence will be heightened in shopping centers and Christmas markets to deter serious criminal activity and ensure public safety. Additionally, extensive road checks will be conducted to address traffic-related incidents, including those caused by impaired drivers....
A year after graduating from college, Chi was adrift. She’d gone from a life of structure to one without guardrails and her mental health was declining. As a result, she distanced herself from friends and family. She left her job as a peer facilitator at a support group for people with depression and bipolar disorder […]
Italy is one of the growing number of countries with its own video game museum, as the GAMM game museum has opened in Rome.
Vector database pioneer is looking to dramatically improve enterprise AI accuracy with cascading retrieval innovations.