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Новости за 03.12.2024

Plos.org 

Correction: Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa

by Noëlie B. Henry, Issiaka Soulama, Samuel S. Sermé, Judith M. Bolscher, Tonnie T. G. Huijs, Aboubacar S. Coulibaly, Salif Sombié, Nicolas Ouédraogo, Amidou Diarra, Soumanaba Zongo, Wamdaogo M. Guelbéogo, Issa Nébié, Sodiomon B. Sirima, Alfred B. Tiono, Alano Pietro, Katharine A. Collins, Koen J. Dechering, Teun Bousema

Plos.org 

Structural comparison of homologous protein-RNA interfaces reveals widespread overall conservation contrasted with versatility in polar contacts

by Ikram Mahmoudi, Chloé Quignot, Carla Martins, Jessica Andreani

Protein-RNA interactions play a critical role in many cellular processes and pathologies. However, experimental determination of protein-RNA structures is still challenging, therefore computational tools are needed for the prediction of protein-RNA interfaces. Although evolutionary pressures can be exploited for structural prediction of protein-protein interfaces, and recent deep learning methods using protein multiple sequence... Читать дальше...

Plos.org 

Expansion of epileptogenic networks via neuroplasticity in neural mass models

by Elif Köksal-Ersöz, Pascal Benquet, Fabrice Wendling

Neuroplasticity refers to functional and structural changes in brain regions in response to healthy and pathological activity. Activity dependent plasticity induced by epileptic activity can involve healthy brain regions into the epileptogenic network by perturbing their excitation/inhibition balance. In this article, we present a new neural mass model, which accounts for neuroplasticity, for investigating the possible mechanisms underlying the epileptogenic network expansion. Читать дальше...

Plos.org 

Hyperspectral imaging in animal coloration research: A user-friendly pipeline for image generation, analysis, and integration with 3D modeling

by Benedict G. Hogan, Mary Caswell Stoddard

Hyperspectral imaging—a technique that combines the high spectral resolution of spectrophotometry with the high spatial resolution of photography—holds great promise for the study of animal coloration. However, applications of hyperspectral imaging to questions about the ecology and evolution of animal color remain relatively rare. The approach can be expensive and unwieldy, and we lack user-friendly pipelines for capturing and analyzing hyperspectral data in the context of animal color. Читать дальше...

Plos.org 

Controlling minor outbreaks is necessary to prepare for major pandemics

by Adam J. Kucharski

Ongoing influenza H5N1 outbreaks highlight the need for timely, scalable interventions that draw on lessons from COVID-19. In particular, successful pandemic preparedness requires early outbreak management, including effective responses targeting spillovers before there is evidence of human-to-human transmission. Ongoing influenza H5N1 outbreaks highlight the need for timely, scalable interventions that draw on lessons from COVID-19. This Perspective discussed that successful... Читать дальше...

Tass.com 

China to become third nuclear superpower by 2030 — expert

Alexander Ageyev also noted that today the international arena was a constantly changing platform of diverse global competition, which "sometimes is a confrontation, sometimes a multi-sphere war, and sometimes multi-sphere cooperation"