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2024
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Новости за 16.12.2024

Plos.org 
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Study on the mechanical behavior and rupture characteristics of coal after thermal damage

by Chuan Li, Yiping Zhang, Haijiao Bu, Hong Lan, Xianwei Heng

High temperature is a critical safety concern that poses challenges to the safe and efficient operation of coal mines. To explore the mechanical behavior and fracture mechanisms of coal exposed to high temperatures, coal samples were subjected to various thermal treatments. After cooling, uniaxial compression tests were performed using an electronic universal testing machine to assess their macroscopic properties. A discrete element numerical model... Читать дальше...

Поэт. Радио Поэт. Стихи поэтов. Русские поэты. Писатели и поэты.
Ушло детство: умер ослик Перри, который стал прототипом для Осла из «Шрека»
«Маленькая принцесса»: Илья Авербух впервые показал лицо дочери Лизы Арзамасовой
Стало известно, как Кейт Миддлтон отметит свой день рождения после борьбы с онкологией
«Арктическое вторжение»: синоптики предупредили расслабившихся россиян о погодных аномалиях
«Это офигенно!» Ирина Хакамада о счастье после четырех разводов
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Associations between dietary mycotoxins exposures and risk of hepatocellular carcinoma in a European cohort

by Inge Huybrechts, Inarie Jacobs, Carine Biessy, Elom K. Aglago, Mazda Jenab, Liesel Claeys, Jiri Zavadil, Corinne Casagrande, Genevieve Nicolas, Ghislaine Scelo, Andrea Altieri, Beatrice Fervers, Isabelle P. Oswald, Julien Vignard, Bernadette Chimera, Maria Santucci de Magistris, Giovanna Masala, Domenico Palli, Lisa Padroni, Jesús Castilla, Ana Jiménez-Zabala, Pauline Frenoy, Francesca Romana Mancini, Xuan Ren, Emily Sonestedt, Paolo Vineis, Alicia Heath, Mårten Werner, Esther Molina-Montes, Christina C. Читать дальше...

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In vitro safety evaluation of dopamine D3R antagonist, R-VK4-116, as a potential medication for the treatment of opioid use disorder

by Rahul M. Nandre, Amy Hauck Newman, Pramod S. Terse

R-VK4-116 is currently being developed as a medication to treat opioid use disorder (OUD). To characterize in vitro safety properties of R-VK4-116, metabolic stability in hepatocytes or liver microsomes, metabolite identification, metabolism/transporter-mediated drug interactions, lysosomal perturbation, mitochondrial toxicity, off-target enzyme effects, cellular and nuclear receptor functional assays, electrophysiological assays, CiPA... Читать дальше...

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Barriers and enablers for implementation of clinical practice guidelines in maternity and neonatal settings: A rapid review

by Kalpana Raghunathan, Christine East, Kritika Poudel

Background

Maternity and neonatal services are rapidly changing in Australia because of evolving needs of the community and patient population. Clinical practice guidelines focused on early interventions and prevention strategies can decrease risk for preventable negative health outcomes in this population. However, despite the existence of several clinical practice guidelines, their translation into practice remains problematic for healthcare services. Читать дальше...

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Right atrial volume index and right atrial volume predict atrial fibrillation recurrence: A meta-analysis

by Jia-Ming Han, Qian Xie, Xiu-Ying Song, Yu-lan Ma

Background

Atrial volume index and atrial volume have recently been identified as predictors of atrial fibrillation (AF) recurrence following electrical cardioversion or radiofrequency ablation. However, most studies have reported the relationship between LAVI/LAV and AF recurrence, whereas there is little information on the relationship between RAVI/RAV and AF recurrence. Therefore, we performed a meta-analysis to assess the relationship... Читать дальше...

В зимнем лесу
Заслуженная артистка России Надежда Чепайкина празднует свой юбилей
Дегустация традиционной рождественской каши пройдет в Пскове 7 января
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Поет зима — аукает, мохнатый лес баюкает...
«Золотая лихорадка»: мир готовится к краху глобальной финансовой системы Запада, — Politico. Очередные "палки в колеса" Трампу?!