Ru24.net News‑life.pro News‑life.org 29ru.net 123ru.market Sportsweek.org Iceprice.info
123ru.net
News in English
Декабрь
2024
23

Новости за 23.12.2024

Plos.org 
En

Non-autonomous insulin signaling delays mitotic progression in C. elegans germline stem and progenitor cells

by Eric Cheng, Ran Lu, Abigail R. Gerhold

Stem and progenitor cell mitosis is essential for tissue development and homeostasis. How these cells ensure proper chromosome segregation, and thereby maintain mitotic fidelity, in the complex physiological environment of a living animal is poorly understood. Here we use in situ live-cell imaging of C. elegans germline stem and progenitor cells (GSPCs) to ask how the signaling environment influences stem and progenitor cell mitosis in vivo. Through... Читать дальше...

Тейлор Свифт возглавила рейтинг «Лучших артистов XXI века»
Страдавший ДЦП актер Рори Сайкс сгорел в своем доме в Калифорнии
Во время пожара в Лос-Анджелесе сгорело издательство, хранившее наследие композитора Арнольда Шенберга
Зимние загадки
Помощь в организации нескольких Презентаций книги для Писателей и Поэтов в Книжных магазинах и других площадках.
Конкурс вокалистов и концертмейстеров Хиблы Герзмава
Plos.org 
En

Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53

by Kenneth Y. Wertheim, Robert Chisholm, Paul Richmond, Dawn Walker

Neuroblastoma is the most common extra-cranial solid tumour in children. Over half of all high-risk cases are expected to succumb to the disease even after chemotherapy, surgery, and immunotherapy. Although the importance of MYCN amplification in this disease is indisputable, the mechanistic details remain enigmatic. Here, we present a multicellular model of neuroblastoma comprising a continuous automaton, discrete cell agents... Читать дальше...

Plos.org 
En

Integration of partially observed multimodal and multiscale neural signals for estimating a neural circuit using dynamic causal modeling

by Jiyoung Kang, Hae-Jeong Park

Integrating multiscale, multimodal neuroimaging data is essential for a comprehensive understanding of neural circuits. However, this is challenging due to the inherent trade-offs between spatial coverage and resolution in each modality, necessitating a computational strategy that combines modality-specific information effectively. This study introduces a dynamic causal modeling (DCM) framework designed to address the challenge of combining partially observed... Читать дальше...

Plos.org 
En

Estimating the distribution of parameters in differential equations with repeated cross-sectional data

by Hyeontae Jo, Sung Woong Cho, Hyung Ju Hwang

Differential equations are pivotal in modeling and understanding the dynamics of various systems, as they offer insights into their future states through parameter estimation fitted to time series data. In fields such as economy, politics, and biology, the observation data points in the time series are often independently obtained (i.e., Repeated Cross-Sectional (RCS) data). RCS data showed that traditional methods for parameter estimation in differential equations... Читать дальше...

Александр Котов: Прокуратура стоит на страже закона и справедливости
В Новосибирске выходцы из Азербайджана оскорбили "русское население" и участников СВО. А посетитель кафе, который сделал замечание был избит толпой
Армянские погромы в Баку – фашизм азербайджанских властей
Выставка рукописных икон открылась в Пскове. ФОТОРЕПОРТАЖ
Центральные дороги чистят от снега в Куньинском районе
В Твери
VOGUE.com 
En

Mouth Taping Sounds Freaky—But There Are Benefits

Perhaps you’ve seen the practice on TikTok or noticed Gwyneth Paltrow talking about it as part of her sleep routine—so what is mouth taping? And more importantly, should you be doing it?