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2024

Новости за 30.12.2024

Plos.org 

Correction: Healthy lifestyle behaviors are major predictors of mental wellbeing during COVID-19 pandemic confinement: A study on adult Arabs in higher educational institutions

by Hashem A. Kilani, Mo’ath F. Bataineh, Ali Al-Nawayseh, Khaled Atiyat, Omar Obeid, Maher M. Abu-Hilal, Taiysir Mansi, Maher Al-Kilani, Mahfoodha Al-Kitani, Majed El-Saleh, Ruba M. Jaber, Ahmad Sweidan, Mawaheb Himsi, Iyad Yousef, Faten Alzeer, Monther Nasrallah, Ayesha S. Al Dhaheri, Abdulsalam Al-Za’abi, Osama Allala, Laila Al-Kilani, Asma M. Alhasan, Mohamed Ghieda, Yasir Najah, Saad Alsheekhly, Ahmad Alhaifi, Raghda Shukri, Jamal Al Adwani, Mostafa Waly, Laila Kilani, Leen H. Kilani, Ahmad S. Читать дальше...

Plos.org 

Fitness landscapes of human microsatellites

by Ryan J. Haasl, Bret A. Payseur

Advances in DNA sequencing technology and computation now enable genome-wide scans for natural selection to be conducted on unprecedented scales. By examining patterns of sequence variation among individuals, biologists are identifying genes and variants that affect fitness. Despite this progress, most population genetic methods for characterizing selection assume that variants mutate in a simple manner and at a low rate. Because these assumptions are violated by repetitive sequences... Читать дальше...

Plos.org 

Marked point process variational autoencoder with applications to unsorted spiking activities

by Ryohei Shibue, Tomoharu Iwata

Spike train modeling across large neural populations is a powerful tool for understanding how neurons code information in a coordinated manner. Recent studies have employed marked point processes in neural population modeling. The marked point process is a stochastic process that generates a sequence of events with marks. Spike train models based on such processes use the waveform features of spikes as marks and express the generative structure of the unsorted spikes without applying spike sorting. Читать дальше...

Plos.org 

Orchard: Building large cancer phylogenies using stochastic combinatorial search

by Ethan Kulman, Rui Kuang, Quaid Morris

Phylogenies depicting the evolutionary history of genetically heterogeneous subpopulations of cells from the same cancer, i.e., cancer phylogenies, offer valuable insights about cancer development and guide treatment strategies. Many methods exist that reconstruct cancer phylogenies using point mutations detected with bulk DNA sequencing. However, these methods become inaccurate when reconstructing phylogenies with more than 30 mutations, or, in some cases, fail to recover a phylogeny altogether.

Plos.org 

BharatSim: An agent-based modelling framework for India

by Philip Cherian, Jayanta Kshirsagar, Bhavesh Neekhra, Gaurav Deshkar, Harshal Hayatnagarkar, Kshitij Kapoor, Chandrakant Kaski, Ganesh Kathar, Swapnil Khandekar, Saurabh Mookherjee, Praveen Ninawe, Riz Fernando Noronha, Pranjal Ranka, Vaibhhav Sinha, Tina Vinod, Chhaya Yadav, Debayan Gupta, Gautam I. Menon

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Plos.org 

Systematic benchmarking of deep-learning methods for tertiary RNA structure prediction

by Akash Bahai, Chee Keong Kwoh, Yuguang Mu, Yinghui Li

The 3D structure of RNA critically influences its functionality, and understanding this structure is vital for deciphering RNA biology. Experimental methods for determining RNA structures are labour-intensive, expensive, and time-consuming. Computational approaches have emerged as valuable tools, leveraging physics-based-principles and machine learning to predict RNA structures rapidly. Despite advancements, the accuracy of computational methods remains modest... Читать дальше...

Duke Basketball Report 

Duke Recruiting: Nikolas Khamenia Update!

Sherman Oaks, CA - January 18: Harvard-Westlake High School guard Nikolas Khamenia, left, battles Notre-Dame High School point guard Angelino Mark for a loose ball during the first half at Notre Dame High School in Sherman Oaks, Wednesday, Jan. 18, 2023. Harvard-Westlake won 85-78 after two overtimes. | Allen J. Schaben / Los Angeles Times via Getty Images

The future Blue Devil is thriving in his senior season

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PocketChess 2.0 vs. Chess Genius 1.2 

Celebrating creativity – Creality Cloud’s Annual Designer Awards 2024

NEWS – As 3D printing technology continues to advance, designers remain the driving force behind the industry’s growth and innovation. Their ingenuity turns abstract ideas into tangible models, fostering progress across industries and making creativity accessible to all. To honor these exceptional talents, Creality Cloud proudly presents the Annual Designer Awards 2024, celebrating its third […]