by Peter S. Andrus, Li-min Yang, Qing-chi Han, Zhi-heng Qi, Zhi-ying Hou, Xiao-nen Wu, Si-yuan Liu, Kun Wang, Jun-hu Chen, Robbie Rae, Christopher M. Wade, Yun-hai Guo, Xiao-nong Zhou
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by Anuja Dokras, Christos Coutifaris, Alan T. Remaley, Nehal N. Mehta, Martin P. Playford, Allen R. Kunselman, Christy C. Stetter, William C. Dodson, Richard S. Legro
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by Conor Hession, Kevin P. Byrne, Kenneth H. Wolfe, Geraldine Butler
The budding yeast Saccharomyces cerevisiae has ‘point’ centromeres, which are much smaller and simpler than centromeres of most other eukaryotes and have a defined DNA sequence. Other yeast taxa have different and highly diverse centromere structures, but a clear picture of how yeast centromeres have evolved is lacking. Here, we investigated nine yeast species in two taxonomic orders that are close outgroups to S. cerevisiae. Читать дальше...
by Gota Morishita, Carsten Murawski, Nitin Yadav, Shinsuke Suzuki
Learning by observing others’ experiences is a hallmark of human intelligence. While the neurocomputational mechanisms underlying observational learning are well understood, less is known about whom people prefer to learn from in the context of observational learning. One hypothesis posits that learners prefer individuals who exhibit a high degree of decision noise, ‘free riding’ on the costly exploration of others. An alternative... Читать дальше...
by Giuseppe Marrazzo, Federico De Martino, Albert Mukovskiy, Martin A. Giese, Beatrice de Gelder
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by Rainey Lyons, Vanja Dukic, David M. Bortz
Characteristics of individuals in a population, such as age and size, play a key role in determining how populations change over time. In contexts of population dynamics, identifying effective model features, such as fecundity and mortality rates, is generally a complex and computationally intensive process, especially when the dynamics are heterogeneous across the population. In this work, we propose a Weak form Scientific Machine Learning-based... Читать дальше...
by Dmitry Amakhin, Anton Chizhov, Guillaume Girier, Mathieu Desroches, Jan Sieber, Serafim Rodrigues
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by Fang Ye, Zhiyi Zhang, Binghao Zhang, Xinyu Li, Jiaxi Deng, Qian Miao, Peiruo Ning, Yunlin Chi, Geng Chen, Zhangsong Wu, Qian Wang, Lezhi Xu, Ningjie Gong, Bangning Cheng, Zhigang Ma, Chungen Qian, Lizhe Zhu, Xin Pan, Yang Du
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by Eudald Pascual-Carreras, Kathrin Garschall, Patrick R. H. Steinmetz
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by Alexandra A.-T. Weber
The traditional pipeline view of academia no longer reflects the reality of scientific careers. Reframing success as a network of paths recognizes excellence in its many forms, fostering a more inclusive, resilient, and socially engaged research culture. The traditional pipeline view of academia no longer reflects the reality of scientific careers. This Perspective reframes success as a network of paths recognizes excellence in its many forms, with the aim of fostering a more inclusive... Читать дальше...
by Longqiang Wang, Xiao Wu, Atanu Paul, Jun Yao, Bin Wang
The breast and ovarian tumor suppressor BRCA1 is a cell cycle-regulated protein and tumors with reduced BRCA1 protein level may share molecular features of BRCA1-mutant tumor and respond to PARPi therapy. Here, we identify that BRCA1 protein stability is controlled through ubiquitin lysine 11 (K11)-linkage modification under the regulation of Cezanne deubiquitinating enzyme, APC/C E3 ligase, and Ube2S E2 conjugating enzyme in a cell cycle-dependent manner. Читать дальше...
by Silke Stertz, Umut Karakus
Zoonotic spillover of influenza A viruses represents a threat to human health. Emerging research suggests that some influenza A viruses can enter host cells via MHC-II across species, potentially increasing spillover risk. Spillover of influenza A viruses from animals to humans represents a threat to our health. This Perspective discusses emerging research that suggests some influenza A viruses can enter host cells via MHC-II across species, reflecting on the... Читать дальше...
Every freelancer eventually asks the same question: Should I niche down or stay broad? The answer depends on a few things.
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New agency to authenticate historical performance claims of advisers, analysts and algotrading brokers
Wales boss Craig Bellamy is looking forward to renewing his rivalry with Canada's Jesse Marsch if he can lead his team to the World Cup.
Lady Helen Taylor, daughter of the Duke and Duchess of Kent, echoed the Princess of Wales' choice of outfit for Together At Christmas
One study found socks contained the highest microbial count of any other once-worn clothing item.
Footage of Kim Kardashian’s brain scan shows low-activity patches common in ageing. These differ entirely from the true holes caused by stroke or infection.
Defense giant Babcock has unveiled its new Autonomous and Remote, Maritime Operational Response – Force (ARMOR Force) concept, a networked architecture of autonomous and remote maritime systems designed to supercharge the UK’s next-generation naval capability.
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Plan ahead this Christmas with our full guide to the final posting dates for 2025
Adani Group has invested Rs 10,000 crores in Telangana over three years. Investments span defense manufacturing, data centers, renewable energy, and cement facilities. This has created over 7000 jobs. The group highlighted its UAV manufacturing facility and highway projects. Adani Cement also established new plants. These developments support Telangana's infrastructure growth and economic goals.
The meeting assumes significance amid lower rates of most of the agricultural commodities even as the government is confident of farm sector growth to be 4 per cent in the current fiscal
Readers of The Local Sweden are fairly upbeat about the year ahead, with many expecting an economic rebound, better personal finances and even a pause in Sweden’s migration clampdown. Although the election is causing concern for many.
