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Новости за 25.07.2024

Plos.org 

Nine quick tips for open meta-analyses

by David Moreau, Kristina Wiebels

Open science principles are revolutionizing the transparency, reproducibility, and accessibility of research. Meta-analysis has become a key technique for synthesizing data across studies in a principled way; however, its impact is contingent on adherence to open science practices. Here, we outline 9 quick tips for open meta-analyses, aimed at guiding researchers to maximize the reach and utility of their findings. We advocate for outlining preregistering clear protocols... Читать дальше...

Plos.org 

Improved protein complex prediction with AlphaFold-multimer by denoising the MSA profile

by Patrick Bryant, Frank Noé

Structure prediction of protein complexes has improved significantly with AlphaFold2 and AlphaFold-multimer (AFM), but only 60% of dimers are accurately predicted. Here, we learn a bias to the MSA representation that improves the predictions by performing gradient descent through the AFM network. We demonstrate the performance on seven difficult targets from CASP15 and increase the average MMscore to 0.76 compared to 0.63 with AFM. We evaluate the procedure on... Читать дальше...

Nasa.gov 

NASA Supports Burst Test for Orbital Reef Commercial Space Station

An element of a NASA-funded commercial space station, Orbital Reef, under development by Blue Origin and Sierra Space, recently completed a full-scale ultimate burst pressure test as part of the agency’s efforts for new destinations in low Earth orbit. This milestone is part of a NASA Space Act Agreement awarded to Blue Origin in 2021. […]

MODELS.com 

From The Bronx to Bulgaria, These Rookies Are Ready for A Runway

Dimana Who: Dimana Sarmenova — @dimana.sarmenova — Bulgarian from Sofia, Bulgaria — born January 30th — 180 cm / 5’11” — she/her. Where: Ivet Fashion (Sofia – mother agency), Muse Management (New York), Brave Model Management (Milan), M + P Models (London) — How did you become a model? For the longest time, my mom […] More...