by Tapan Bhattacharyya, Niamh Murphy, Michael A. Miles
Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, remains a public health issue in endemic regions of the Americas, and is becoming globalised due to migration. In the chronic phase, 2 accordant serological tests are required for diagnosis. In addition to “in-house” assays, commercial tests are available (principally ELISA and rapid diagnostic tests). Herein, we discuss the discovery era of defined T. cruzi serological... Читать дальше...
by The PLOS Neglected Tropical Diseases Editors
by Jonathan Nicholas Lamb, Jonathan Thomas Evans, Samuel Relton, Michael Richard Whitehouse, J Mark Wilkinson, Hemant Pandit
Читать дальше...
by Marie-Cécile Dupas, Francesco Pinotti, Chaitanya Joshi, Madhvi Joshi, Weerapong Thanapongtharm, Madhur Dhingra, Damer Blake, Fiona Tomley, Marius Gilbert, Guillaume Fournié
Читать дальше...
by Safiye Celik, Jan-Christian Hütter, Sandra Melo Carlos, Nathan H. Lazar, Rahul Mohan, Conor Tillinghast, Tommaso Biancalani, Marta M. Fay, Berton A. Earnshaw, Imran S. Haque
Читать дальше...
by Elin K. Falla, Nik J. Cunniffe
Plant viruses threaten food security and are often transmitted by insect vectors. Non-persistently transmitted (NPT) plant viruses are transmitted almost exclusively by aphids. Because virions attach to the aphid’s stylet (mouthparts) and are acquired and inoculated via brief epidermal probes, the aphid–virus interaction is highly transient, with a very short aphid virus retention time. Many NPT viruses manipulate their host plant’s phenotype to change aphid behaviour to optimise virus transmission. Читать дальше...
by Bertram Klinger, Isabel Rausch, Anja Sieber, Helmut Kutz, Vanessa Kruse, Marieluise Kirchner, Philipp Mertins, Arnd Kieser, Nils Blüthgen, Dieter Kube
Читать дальше...
by Eloïse C. Déaux, Théophane Piette, Florence Gaunet, Thierry Legou, Luc Arnal, Anne-Lise Giraud
Читать дальше...
by Vanessa Kay Miller, Kendal Broadie
The optimization of brain circuit connectivity based on initial environmental input occurs during critical periods characterized by sensory experience-dependent, temporally restricted, and transiently reversible synapse elimination. This precise, targeted synaptic pruning mechanism is mediated by glial phagocytosis. Serotonin signaling has prominent, foundational roles in the brain, but functions in glia, or in experience-dependent brain circuit synaptic connectivity remodeling... Читать дальше...
Scott Snyder, CEO of Bad Ass Coffee of Hawaii, shares how he's helped take the already well-loved brand to the mainstream.
The dream role for a food-lover and travel enthusiast allows them to visit some of the most stunning destinations in the world while sharing their adventures on social media.
The so-called great minds in economics and finance claim that gold is a “barbarous relic” or a “shiny,” worthless rock. Gold is neither. Despite the steady attacks on its integrity, gold remains a good place to put one's money.
The tech giant says we are moving to a "fundamentally new age" of "persistent" AI tools.
Andy Moore has become a familiar face on Emmerdale as PC Mike Swirling, but away from the ITV soap, the actor - who has a different real name - has an impressive career
India will fabricate its first chip in two years, Commerce Minister Piyush Goyal told CNBC during a one-on-one interview with CNBC in New York.
Macworld
When the iPhone 16 handsets were unveiled last month, there weren’t many surprises. Most of the upgrades had been leaked long before, or accurately guessed by well-informed analysts. But not everything we heard before the event proved to be correct.
One theory, supported by seemingly robust evidence, was that the new phones would bring a substantial increase in wired charging speed, all the way up to 45W if the power brick and other accessories supported it. (The... Читать дальше...
Outspoken advocate for Israel and the Jewish people.
Yes, we’ve a wait until the spectacle of the riding itself, but there are eight days of digging ahead of us before the first women will compete at Red Bull...
M., kidnapped from her home in Sinjar as a ten year old girl, was lured into Gaza and remained stuck there for years.
The New England Patriots backed Jacoby Brissett as the starting quarterback after their ugly loss last Sunday and a segment of fans agreed with that decision but for different reasons. Despite Brissett’s poor play, head coach Jerod Mayo dismissed the idea of replacing the veteran with rookie Drake Maye. There’s a logical rationale for the […]
Today IAEA representatives have the opportunity to verify the compliance of the BelNPP with international requirements, Belarusian Deputy Prime Minister Viktor Karankevich said as he met with IAEA Director General Rafael Grossi.